The persistence of a silent memory

Mikel Zaratiegui, Robert Martienssen

Research output: Contribution to journalArticlepeer-review


One of the most striking properties of RNA interference (RNAi) in Caenorhabditis elegans is its persistence in offspring after the triggering double-stranded RNA (dsRNA) has disappeared. A new study reveals that a heterochromatic silencing mark is deposited around the targets of RNAi and is transmitted through generations. These results show that RNAi can induce stable and heritable chromatin modifications in animals.

Original languageEnglish (US)
Pages (from-to)118-119
Number of pages2
JournalNature Genetics
Issue number2
StatePublished - Feb 2012

All Science Journal Classification (ASJC) codes

  • Genetics


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