Transcranial magnetic stimulation: Studying the brain-behaviour relationship by induction of 'virtual lesions'

Alvaro Pascual-Leone, David Bartres-Faz, Julian P. Keenan

Research output: Contribution to journalArticle

314 Scopus citations


Transcranial magnetic stimulation (TMS) provides a non-invasive method of induction of a focal current in the brain and transient modulation of the function of the targeted cortex. Despite limited understanding about focality and mechanisms of action, TMS provides a unique opportunity of studying brain behaviour relations in normal humans. TMS can enhance the results of other neuroimaging techniques by establishing the causal link between brain activity and task performance, and by exploring functional brain connectivity.

Original languageEnglish
Pages (from-to)1229-1238
Number of pages10
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Issue number1387
StatePublished - Jul 29 1999


All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)


  • Brain-behaviour relation
  • Non-invasive
  • Transcranial magnetic stimulation

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