Transition metal dichalcogenides as cell culture platforms

A. Palumbo, F. Tourlomousis, R. Chang, E. H. Yang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Transition metal dichalcogenides (TMDs) are emerging two-dimensional (2D) nanomaterials with unique material properties. While the role of TMDs in biomedical applications has been investigated, TMDs as engineered biological substrates have yet to be systematically studied. In this work, the design and fabrication of TMDs (WS2 and M0S2) yield cell culture platforms for cell adhesion with downstream analysis of cellular morphometric features (i.e., cell area and eccentricity). It is observed that the presence of TMDs improves cell adhesion and viability on cytotoxic SiC>2. Furthermore, cell morphology is determined to be more elongated on M0S2 than WS2. Though there is no significant difference in the average cell area between M0S2 and WS2, a larger distribution of cell areas is observed for the WS2 sample.

Original languageEnglish
Title of host publicationAdvanced Materials - TechConnect Briefs 2017
EditorsMatthew Laudon, Fiona Case, Bart Romanowicz
PublisherTechConnect
Pages99-102
Number of pages4
ISBN (Electronic)9780997511789
StatePublished - 2017
Event11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference - Washington, United States
Duration: May 14 2017May 17 2017

Publication series

NameAdvanced Materials - TechConnect Briefs 2017
Volume1

Conference

Conference11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference
Country/TerritoryUnited States
CityWashington
Period5/14/175/17/17

ASJC Scopus subject areas

  • Fuel Technology
  • Surfaces, Coatings and Films
  • Biotechnology
  • Fluid Flow and Transfer Processes

Keywords

  • Cell adhesion
  • Cell-substrate interactions
  • Fibroblast cells
  • Morphometric features
  • Transition metal dichalcogenides

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