Use of plant roots for phytoremediation and molecular farming

Doloressa Gleba, Nikolai V. Borisjuk, Ludmyla G. Borisjuk, Ralf Kneer, Alexander Poulev, Marina Skarzhinskaya, Slavik Dushenkov, Sithes Logendra, Yuri Y. Gleba, Ilya Raskin

Research output: Contribution to journalArticlepeer-review

187 Scopus citations


Alternative agriculture, which expands the uses of plants well beyond food and fiber, is beginning to change plant biology. Two plant-based biotechnologies were recently developed that take advantage of the ability of plant roots to absorb or secrete various substances. They are (i) phytoextraction, the use of plants to remove pollutants from the environment and (ii) rhizosecretion, a subset of molecular farming, designed to produce and secrete valuable natural products and recombinant proteins from roots. Here we discuss recent advances in these technologies and assess their potential in soil remediation, drug discovery, and molecular farming.

Original languageAmerican English
Pages (from-to)5973-5977
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number11
StatePublished - May 25 1999

ASJC Scopus subject areas

  • General


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