Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids: a Preliminary Probe of Feasibility and Effectiveness

Megan S. Chesin; Chintan V. Dave; Catherine Myers; Barbara Stanley; Anna Kline; Maureen Monahan; Miriam Latorre; Lauren M.St Hill; Rachael B. Miller; Arlene R. King; Dianna R. Boschulte; Megan Sedita; Alejandro Interian

doi:https://doi.org/10.1007/s11469-022-00817-x

Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids: a Preliminary Probe of Feasibility and Effectiveness

Megan S. Chesin, Chintan V. Dave, Catherine Myers, Barbara Stanley, Anna Kline, Maureen Monahan, Miriam Latorre, Lauren M.St Hill, Rachael B. Miller, Arlene R. King, Dianna R. Boschulte, Megan Sedita, Alejandro Interian

Research output: Contribution to journal › Article › peer-review

Abstract

Knowledge of how to effectively prevent suicide attempt (SA) in high suicide–risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive mindfulness-based cognitive therapy to prevent suicide among high suicide–risk veterans (n = 18 per treatment condition), MBCT-S reduced the likelihood of SA and acute psychiatric hospitalization over 12-month follow-up. Those in MBCT-S had a relative risk of 17% and 42% for SA and hospitalization (p =.09,.02), respectively, compared to those receiving enhanced treatment as usual (eTAU) alone. Rates of opioid misuse during follow-up were more than halved with the addition of MBCT-S to eTAU (p =.08). Meanwhile, among trial participants who did not misuse opioids (n = 104), RRs of 64% and 77% for SA and hospitalization (p =.28,.33), respectively, were found with MBCT-S compared to eTAU. An MBCT-S trial with greater power is warranted in this population.

Original language	American English
Journal	International Journal of Mental Health and Addiction
DOIs	https://doi.org/10.1007/s11469-022-00817-x
State	Accepted/In press - 2022
Externally published	Yes

ASJC Scopus subject areas

Psychiatry and Mental health

Keywords

High suicide–risk patients
Mindfulness-based cognitive therapy to prevent suicide
Opioid misuse
Veterans

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https://doi.org/10.1007/s11469-022-00817-x

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Chesin, M. S., Dave, C. V., Myers, C., Stanley, B., Kline, A., Monahan, M., Latorre, M., Hill, L. M. S., Miller, R. B., King, A. R., Boschulte, D. R., Sedita, M., & Interian, A. (Accepted/In press). Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids: a Preliminary Probe of Feasibility and Effectiveness. International Journal of Mental Health and Addiction. https://doi.org/10.1007/s11469-022-00817-x

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title = "Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids: a Preliminary Probe of Feasibility and Effectiveness",

abstract = "Knowledge of how to effectively prevent suicide attempt (SA) in high suicide–risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive mindfulness-based cognitive therapy to prevent suicide among high suicide–risk veterans (n = 18 per treatment condition), MBCT-S reduced the likelihood of SA and acute psychiatric hospitalization over 12-month follow-up. Those in MBCT-S had a relative risk of 17% and 42% for SA and hospitalization (p =.09,.02), respectively, compared to those receiving enhanced treatment as usual (eTAU) alone. Rates of opioid misuse during follow-up were more than halved with the addition of MBCT-S to eTAU (p =.08). Meanwhile, among trial participants who did not misuse opioids (n = 104), RRs of 64% and 77% for SA and hospitalization (p =.28,.33), respectively, were found with MBCT-S compared to eTAU. An MBCT-S trial with greater power is warranted in this population.",

keywords = "High suicide–risk patients, Mindfulness-based cognitive therapy to prevent suicide, Opioid misuse, Veterans",

author = "Chesin, {Megan S.} and Dave, {Chintan V.} and Catherine Myers and Barbara Stanley and Anna Kline and Maureen Monahan and Miriam Latorre and Hill, {Lauren M.St} and Miller, {Rachael B.} and King, {Arlene R.} and Boschulte, {Dianna R.} and Megan Sedita and Alejandro Interian",

note = "Funding Information: This work was supported by a grant from the US Department of Veterans Affairs, Health Services Research and Development Service (IIR 12–134). Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2022",

doi = "https://doi.org/10.1007/s11469-022-00817-x",

language = "American English",

journal = "International Journal of Mental Health and Addiction",

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Chesin, MS, Dave, CV, Myers, C, Stanley, B, Kline, A, Monahan, M, Latorre, M, Hill, LMS, Miller, RB, King, AR, Boschulte, DR, Sedita, M & Interian, A 2022, 'Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids: a Preliminary Probe of Feasibility and Effectiveness', International Journal of Mental Health and Addiction. https://doi.org/10.1007/s11469-022-00817-x

TY - JOUR

T1 - Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids

T2 - a Preliminary Probe of Feasibility and Effectiveness

AU - Chesin, Megan S.

AU - Dave, Chintan V.

AU - Myers, Catherine

AU - Stanley, Barbara

AU - Kline, Anna

AU - Monahan, Maureen

AU - Latorre, Miriam

AU - Hill, Lauren M.St

AU - Miller, Rachael B.

AU - King, Arlene R.

AU - Boschulte, Dianna R.

AU - Sedita, Megan

AU - Interian, Alejandro

N1 - Funding Information: This work was supported by a grant from the US Department of Veterans Affairs, Health Services Research and Development Service (IIR 12–134). Publisher Copyright: © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2022

Y1 - 2022

N2 - Knowledge of how to effectively prevent suicide attempt (SA) in high suicide–risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive mindfulness-based cognitive therapy to prevent suicide among high suicide–risk veterans (n = 18 per treatment condition), MBCT-S reduced the likelihood of SA and acute psychiatric hospitalization over 12-month follow-up. Those in MBCT-S had a relative risk of 17% and 42% for SA and hospitalization (p =.09,.02), respectively, compared to those receiving enhanced treatment as usual (eTAU) alone. Rates of opioid misuse during follow-up were more than halved with the addition of MBCT-S to eTAU (p =.08). Meanwhile, among trial participants who did not misuse opioids (n = 104), RRs of 64% and 77% for SA and hospitalization (p =.28,.33), respectively, were found with MBCT-S compared to eTAU. An MBCT-S trial with greater power is warranted in this population.

AB - Knowledge of how to effectively prevent suicide attempt (SA) in high suicide–risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive mindfulness-based cognitive therapy to prevent suicide among high suicide–risk veterans (n = 18 per treatment condition), MBCT-S reduced the likelihood of SA and acute psychiatric hospitalization over 12-month follow-up. Those in MBCT-S had a relative risk of 17% and 42% for SA and hospitalization (p =.09,.02), respectively, compared to those receiving enhanced treatment as usual (eTAU) alone. Rates of opioid misuse during follow-up were more than halved with the addition of MBCT-S to eTAU (p =.08). Meanwhile, among trial participants who did not misuse opioids (n = 104), RRs of 64% and 77% for SA and hospitalization (p =.28,.33), respectively, were found with MBCT-S compared to eTAU. An MBCT-S trial with greater power is warranted in this population.

KW - High suicide–risk patients

KW - Mindfulness-based cognitive therapy to prevent suicide

KW - Opioid misuse

KW - Veterans

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U2 - https://doi.org/10.1007/s11469-022-00817-x

DO - https://doi.org/10.1007/s11469-022-00817-x

M3 - Article

SN - 1557-1874

JO - International Journal of Mental Health and Addiction

JF - International Journal of Mental Health and Addiction

ER -

Using Mindfulness-Based Cognitive Therapy to Prevent Suicide Among High Suicide–Risk Patients Who Also Misuse Opioids: a Preliminary Probe of Feasibility and Effectiveness

Abstract

ASJC Scopus subject areas

Keywords

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