XANES in nanobiology

Rebecca A. Metzler, Ronke M. Olabisi, Mike Abrecht, Daniel Ariosa, Christopher J. Johnson, Benjamin Gilbert, Bradley H. Frazer, Susan N. Coppersmith, P. U.P.A. Gilbert

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The combination of spectroscopy and microscopy enables unprecedented insights into the molecular and crystal structures of organic and inorganic materials, and their interfaces. This is relevant to the field of biomaterials in general and biominerals in particular. In this framework, we extensively analyzed various proteins, minerals and biominerals. Here we present two novel observations: x-ray absorption near-edge structure (XANES) spectroscopy at the carbon K-edge is sensitive to protein misfolding and aggregation into amyloid fibrils, and to the polar and azimuthal rotation of the CaCO3 polymorph aragonite.

Original languageEnglish (US)
Title of host publicationX-RAY ABSORPTION FINE STRUCTURE - XAFS13
Subtitle of host publication13th International Conference
Pages51-55
Number of pages5
DOIs
StatePublished - 2007
Externally publishedYes
EventX-RAY ABSORPTION FINE STRUCTURE - XAFS13: 13th International Conference - Stanford, CA, United States
Duration: Jul 9 2006Jul 14 2006

Publication series

NameAIP Conference Proceedings
Volume882

Other

OtherX-RAY ABSORPTION FINE STRUCTURE - XAFS13: 13th International Conference
Country/TerritoryUnited States
CityStanford, CA
Period7/9/067/14/06

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Keywords

  • Aggregation
  • Cross-Β
  • Nacre
  • Orientation
  • Protein misfolding
  • X-PEEM
  • XANES

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